TAF7L

Across TCGA patient cohorts, TAF7L mutation is significantly associated with the RNA expression of many other genes, with 3,667 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF7L-associated genes across cancer lineages are RNA5SP463, PSMD9, and RNU6-413P. Each is linked with TAF7L in more than 2 cancer types. Because this analysis shows association rather than direction, both TAF7L-to-partner and partner-to-TAF7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP463 grouped by TAF7L-low versus TAF7L-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF7L→partner) and Y-score (partner→TAF7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP463 →	+0.196	+3.201	<.001	.009	3	3
UCEC	PSMD9 →	+0.433	+2.662	<.001	<.001	3	3
LUAD	RNU6-413P →	+0.150	+5.339	<.001	.001	3	2
SKCM	HAO2-IT1 →	+0.123	+2.862	.001	.005	3	2
UCEC	HIKESHI →	+0.340	+3.502	.006	.002	3	2
UCEC	FAM177A1 →	+0.459	+3.732	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,667 associations by consensus.

RNA5SP463 by TAF7L expression — LUAD

Explore this box plot interactively →