TAF7L

Across TCGA pan-cancer cohorts, TAF7L RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated TAF7L data layer compared with 9 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TAF7L RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TAF7L expression acts as an unfavorable survival marker, although some lineages such as BLCA and KIRP show a favorable association.

KIRC, BLCA, and LGG are the cancer types where TAF7L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.542	0.701	<.001	81	view →
BLCA	OS	Median	III,IV	0.664	0.485	.001	53	view →
LGG	DFS	Median	All	0.642	0.823	<.001	53	view →
KIRP	DFS	Tertile	II,III,IV	1.000	0.157	.003	48	view →
KICH	DFS	Quartile	II,III,IV	0.266	0.925	.001	43	view →
BRCA	OS	Tertile	II,III,IV	0.451	0.627	.002	33	view →
SKCM	OS	Tertile	All	0.699	0.842	<.001	31	view →
SCLC	DFS	Quartile	All	0.683	0.315	.002	31	view →
ACC	OS	Quartile	All	0.321	0.844	.005	24	view →
LIHC	DFS	Tertile	III,IV	0.468	0.229	.002	19	view →
THCA	OS	Quartile	II,III,IV	0.815	1.000	.020	15	view →
STAD	OS	Median	III,IV	0.494	0.225	.008	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

TAF7L–KIRC (DFS)

Open the KIRC breakdown →