TAF7L

Across TCGA cell cohorts, TAF7L mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAF7L-associated genes across cancer lineages are ECRG4, CDX4, and TAFA1. Each is linked with TAF7L in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF7L-to-partner and partner-to-TAF7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ECRG4 grouped by TAF7L-low versus TAF7L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF7L→partner) and Y-score (partner→TAF7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ECRG4 →	+0.120	+3.373	.004	.007	3	1
LARGE_INTESTINE	CDX4 →	+0.007	+3.217	.001	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1
LARGE_INTESTINE	BPIFA1 →	+0.114	+3.103	.003	.004	3	1
LARGE_INTESTINE	KRTAP10-2 →	+0.044	+2.994	.001	.006	3	1
LARGE_INTESTINE	C16orf96 →	+0.527	+3.520	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

ECRG4 by TAF7L expression — LARGE_INTESTINE

Explore this box plot interactively →