TAF6L

Across TCGA patient cohorts, TAF6L mutation is significantly associated with the RNA expression of many other genes, with 1,380 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF6L-associated genes across cancer lineages are SRSF6P1, MIR3667, and RNU7-138P. Each is linked with TAF6L in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF6L-to-partner and partner-to-TAF6L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SRSF6P1 grouped by TAF6L-low versus TAF6L-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF6L→partner) and Y-score (partner→TAF6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	SRSF6P1 →	+0.050	+4.384	<.001	.008	3	2
STAD	MIR3667 →	+0.673	+4.440	<.001	.006	3	2
COAD	RNU7-138P →	+0.332	+4.409	<.001	.004	3	2
UCEC	FAM177A1P1 →	+0.125	+2.281	.004	.001	3	2
UCEC	ZNF433-AS1 →	+0.505	+2.839	<.001	.001	3	2
UCEC	LINC01758 →	+0.176	+2.356	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,380 associations by consensus.

SRSF6P1 by TAF6L expression — CESC

Explore this box plot interactively →