TAF6L

Across TCGA cell cohorts, TAF6L mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAF6L-associated genes across cancer lineages are GHSR, OR5P3, and USP17L13. Each is linked with TAF6L in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF6L-to-partner and partner-to-TAF6L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHSR grouped by TAF6L-low versus TAF6L-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF6L→partner) and Y-score (partner→TAF6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GHSR →	+0.039	+4.017	<.001	.007	3	1
OESOPHAGUS	OR5P3 →	+0.123	+4.017	<.001	.007	3	1
BLOOD_Leukemia	USP17L13 →	+0.004	+4.969	<.001	.003	3	1
BLOOD_Leukemia	USP17L17 →	+0.005	+5.569	<.001	.001	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1
OVARY	KRT73 →	+0.016	+5.196	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

GHSR by TAF6L expression — OESOPHAGUS

Explore this box plot interactively →