TAF1D

Across TCGA patient cohorts, TAF1D mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF1D-associated genes across cancer lineages are Ku80, Annexin_VII, and EGFR_pY1068. Each is linked with TAF1D in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF1D-to-partner and partner-to-TAF1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by TAF1D-low versus TAF1D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF1D→partner) and Y-score (partner→TAF1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.260	+2.183	.035	.035	3	1
UCEC	Annexin_VII →	-0.144	-3.321	.048	.010	3	1
UCEC	EGFR_pY1068 →	-0.285	-3.321	.030	.010	2	1
UCEC	mTOR_pS2448 →	-0.175	-2.980	.025	.036	2	1
UCEC	p38-MAPK_pT180_Y182 →	-0.617	-3.308	.008	.010	2	1
UCEC	PCNA →	+0.232	+3.321	.041	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Ku80 by TAF1D expression — UCEC

Explore this box plot interactively →