TAF1D

Across TCGA pan-cancer cohorts, TAF1D RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of TAF1D’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TAF1D RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAF1D is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, HNSC, and COAD are the cancer types where TAF1D tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAF1D RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+1.416	<.001	12	view →
HNSC	Male	III,IV	+1.001	<.001	12	view →
COAD	Male	II,III,IV	+1.388	<.001	9	view →
LIHC	Female	II,III,IV	+1.266	<.001	9	view →
LUAD	Male	II,III,IV	+1.150	<.001	9	view →
STAD	Male	II,III,IV	+1.139	<.001	9	view →
KIRP	All	All	+0.614	<.001	8	view →
BLCA	All	III,IV	+0.532	.001	8	view →
READ	Female	All	+1.319	<.001	7	view →
THCA	Male	All	+0.424	<.001	7	view →
CHOL	Female	All	+2.983	<.001	5	view →
ESCA	All	All	+1.016	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

TAF1D–KIRC

Open the KIRC breakdown →