TAF1C

Across TCGA pan-cancer cohorts, TAF1C mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TAF1C data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TAF1C mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TAF1C expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

HNSC, LSCC, and CCRCC are the cancer types where TAF1C mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.873	0.496	.002	23	view →
LSCC	DFS	Median	II,III,IV	0.914	0.600	.004	22	view →
CCRCC	DFS	Quartile	III,IV	0.135	0.789	.038	6	view →
GBM	OS	Median	All	0.694	0.348	.012	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TAF1C–HNSC (DFS)

Open the HNSC breakdown →