TAF1C

Across TCGA patient cohorts, TAF1C mutation is significantly associated with the RNA expression of many other genes, with 4,194 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF1C-associated genes across cancer lineages are MAP2K1, UBE2L3, and CNEP1R1. Each is linked with TAF1C in more than 3 cancer types. Because this analysis shows association rather than direction, both TAF1C-to-partner and partner-to-TAF1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAP2K1 grouped by TAF1C-low versus TAF1C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF1C→partner) and Y-score (partner→TAF1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAP2K1 →	+0.589	+3.191	<.001	<.001	3	3
UCEC	UBE2L3 →	+0.332	+2.021	<.001	<.001	3	3
SKCM	CNEP1R1 →	+0.492	+3.706	.007	<.001	3	3
SKCM	ANXA2P1 →	+0.302	+3.182	.006	.009	3	3
SKCM	NUDC →	+0.412	+3.341	.004	.005	3	3
UCEC	CDC45 →	+0.680	+2.375	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,194 associations by consensus.

MAP2K1 by TAF1C expression — UCEC

Explore this box plot interactively →