TAF1C

Across TCGA cell cohorts, TAF1C mutation is significantly associated with the RNA expression of many other genes, with 484 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAF1C-associated genes across cancer lineages are PSG11, CRNN, and DEFB108B. Each is linked with TAF1C in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF1C-to-partner and partner-to-TAF1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSG11 grouped by TAF1C-low versus TAF1C-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF1C→partner) and Y-score (partner→TAF1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PSG11 →	+0.099	+4.070	.003	.003	3	1
BLOOD_Leukemia	CRNN →	+0.049	+3.475	<.001	.006	3	1
BLOOD_Leukemia	DEFB108B →	+0.106	+3.684	<.001	.004	3	1
BLOOD_Leukemia	GUCA2A →	+0.026	+3.969	<.001	.009	3	1
BLOOD_Leukemia	TAS2R39 →	+0.073	+3.339	<.001	.006	3	1
LARGE_INTESTINE	ZBED4 →	+0.584	+3.137	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 484 associations by consensus.

PSG11 by TAF1C expression — LUNG_SCLC

Explore this box plot interactively →