TAF1B

Across TCGA patient cohorts, TAF1B mutation is significantly associated with the RNA expression of many other genes, with 1,230 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF1B-associated genes across cancer lineages are RNU6ATAC11P, RNU6-782P, and MIR4295. Each is linked with TAF1B in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF1B-to-partner and partner-to-TAF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6ATAC11P grouped by TAF1B-low versus TAF1B-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF1B→partner) and Y-score (partner→TAF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RNU6ATAC11P →	+0.281	+5.039	<.001	.009	3	2
LGG	RNU6-782P →	+0.369	+6.632	<.001	.001	3	2
LGG	MIR4295 →	+0.385	+6.032	<.001	.002	3	2
LGG	RN7SL557P →	+0.212	+5.846	<.001	.003	3	2
LUSC	NBEAP5 →	+0.374	+5.273	<.001	.006	3	2
BLCA	MTCO3P1 →	+0.057	+4.568	.005	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,230 associations by consensus.

RNU6ATAC11P by TAF1B expression — LGG

Explore this box plot interactively →