TAF1B

Across TCGA pan-cancer cohorts, TAF1B RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of TAF1B’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TAF1B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAF1B is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

HNSC, BLCA, and LIHC are the cancer types where TAF1B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAF1B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+0.755	<.001	11	view →
BLCA	All	III,IV	+0.831	<.001	10	view →
LIHC	Male	All	+0.817	<.001	9	view →
KICH	Female	II,III,IV	−2.075	<.001	8	view →
COAD	Male	All	+0.598	<.001	8	view →
STAD	All	II,III,IV	+0.671	<.001	6	view →
CHOL	All	All	+1.568	<.001	5	view →
READ	All	III,IV	+1.014	.004	5	view →
LUAD	Male	All	+0.430	.001	5	view →
LUSC	Male	All	+0.631	<.001	4	view →
BRCA	All	II,III,IV	+0.259	.001	4	view →
KIRP	All	All	−0.336	.015	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

TAF1B–HNSC

Open the HNSC breakdown →