TAF1B

Across TCGA patient cohorts, TAF1B mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF1B-associated genes across cancer lineages are Caspase-7-cleavedD198, ERK2, and FoxM1. Each is linked with TAF1B in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF1B-to-partner and partner-to-TAF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by TAF1B-low versus TAF1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF1B→partner) and Y-score (partner→TAF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.499	+2.242	.019	.005	3	2
UCEC	ERK2 →	+0.140	+1.925	.044	.005	3	1
UCEC	FoxM1 →	+0.197	+1.925	.034	.005	3	1
UCEC	mTOR_pS2448 →	-0.112	-1.886	.037	.015	3	1
UCEC	Myosin-IIa_pS1943 →	+0.175	+2.222	.018	.010	3	1
UCEC	Myosin-IIa →	+0.177	+2.711	.011	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Caspase-7-cleavedD198 by TAF1B expression — UCEC

Explore this box plot interactively →