TAF1B

Across TCGA cell cohorts, TAF1B mutation is significantly associated with the drug of many other genes, with 27 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAF1B-associated genes across cancer lineages are JNJ38877605, Brivanib, and Dinaciclib. Each is linked with TAF1B in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF1B-to-partner and partner-to-TAF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNJ38877605 grouped by TAF1B-low versus TAF1B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF1B→partner) and Y-score (partner→TAF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	JNJ38877605 →	+0.426	+2.786	.013	.037	3	1
LARGE_INTESTINE	Brivanib →	+0.360	+2.652	.039	.045	3	1
LARGE_INTESTINE	Dinaciclib →	+0.592	+2.646	.021	.047	2	1
LARGE_INTESTINE	AZD5991 →	+1.476	+2.649	<.001	.046	2	1
LARGE_INTESTINE	GSK2276186C →	+0.465	+2.649	.045	.046	2	1
LARGE_INTESTINE	Oxaliplatin →	+0.613	+2.649	.020	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

JNJ38877605 by TAF1B expression — LARGE_INTESTINE

Explore this box plot interactively →