TAF15

Across TCGA cell cohorts, TAF15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,510 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAF15-associated GO terms across cancer lineages are Negative regulation of mitotic cell cycle, Lagging strand elongation, and Positive regulation of mitotic cytokinesis. Each is linked with TAF15 in more than 16 cancer types. Because this analysis shows association rather than direction, both TAF15-to-partner and partner-to-TAF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mitotic cell cycle grouped by TAF15-low versus TAF15-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF15→partner) and Y-score (partner→TAF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of mitotic cell cycle →	+0.055	+0.769	<.001	<.001	3	17
BLOOD_Myeloma	Lagging strand elongation →	+0.142	+0.901	<.001	<.001	3	16
PANCREAS	Positive regulation of mitotic cytokinesis →	+0.187	+0.763	<.001	<.001	3	15
PANCREAS	DNA strand elongation →	+0.184	+1.038	<.001	<.001	3	15
SOFT_TISSUE	Replication fork processing →	+0.093	+0.834	<.001	<.001	3	15
PANCREAS	Mitotic DNA replication checkpoint signaling →	+0.203	+0.931	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,510 associations by consensus.

Negative regulation of mitotic cell cycle by TAF15 expression — LARGE_INTESTINE

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