TAF15

Across TCGA pan-cancer cohorts, TAF15 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of TAF15’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TAF15 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAF15 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, LIHC, and KICH are the cancer types where TAF15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAF15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.535	<.001	10	view →
LIHC	Male	All	+0.679	<.001	8	view →
KICH	Female	All	−1.189	<.001	7	view →
STAD	All	II,III,IV	+0.773	<.001	7	view →
LUSC	Male	II,III,IV	+0.733	<.001	7	view →
COAD	All	II,III,IV	+0.386	.001	6	view →
CHOL	Male	All	+1.616	<.001	5	view →
KIRP	All	IV	+0.832	.005	3	view →
ESCA	All	All	+0.726	.021	3	view →
BLCA	Female	All	+0.639	.004	3	view →
READ	All	III,IV	+0.944	.004	2	view →
LUAD	All	II,III,IV	+0.404	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

TAF15–HNSC

Open the HNSC breakdown →