TAF15

Across TCGA cell cohorts, TAF15 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TAF15-associated genes across cancer lineages are HHLA1, CCKAR, and NPY2R. Each is linked with TAF15 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF15-to-partner and partner-to-TAF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HHLA1 grouped by TAF15-low versus TAF15-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF15→partner) and Y-score (partner→TAF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HHLA1 →	+0.011	+4.551	<.001	.004	3	1
BLOOD_Leukemia	CCKAR →	+0.043	+4.409	<.001	.005	3	1
BLOOD_Leukemia	NPY2R →	+0.094	+4.539	<.001	.007	3	1
BLOOD_Leukemia	LYPD2 →	+0.118	+4.152	<.001	.009	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1
STOMACH	ASB17 →	+0.035	+4.432	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

HHLA1 by TAF15 expression — BLOOD_Leukemia

Explore this box plot interactively →