TAF10

Across TCGA pan-cancer cohorts, TAF10 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated TAF10 data layer compared with 4 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TAF10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TAF10 expression acts as an unfavorable survival marker, although some lineages such as SCLC and BRCA show a favorable association.

KIRC, ACC, and LIHC are the cancer types where TAF10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.535	0.728	<.001	200	view →
ACC	DFS	Median	All	0.240	0.644	<.001	98	view →
LIHC	OS	Median	III,IV	0.312	0.715	<.001	64	view →
LUAD	DFS	Tertile	All	0.675	0.839	.003	43	view →
SCLC	OS	Median	All	0.706	0.427	.001	34	view →
BRCA	OS	Median	All	0.673	0.509	<.001	32	view →
LGG	DFS	Median	All	0.782	0.879	<.001	28	view →
KICH	DFS	Median	III,IV	0.373	1.000	.008	28	view →
LAML	DFS	Quartile	All	0.297	0.513	.008	18	view →
LUSC	OS	Tertile	III,IV	0.225	0.529	.004	16	view →
BLCA	OS	Quartile	II,III,IV	0.765	0.615	.013	12	view →
KIRP	OS	Tertile	II,III,IV	0.464	1.000	.013	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

TAF10–KIRC (OS)

Open the KIRC breakdown →