TAF10

Across TCGA pan-cancer cohorts, TAF10 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of TAF10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TAF10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAF10 is over-expressed in tumor.

KIRC, KIRP, and COAD are the cancer types where TAF10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAF10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.668	<.001	12	view →
KIRP	Female	II,III,IV	+0.845	<.001	11	view →
COAD	Female	II,III,IV	+0.654	<.001	11	view →
LIHC	Male	II,III,IV	+1.225	<.001	9	view →
STAD	All	II,III,IV	+0.599	<.001	8	view →
HNSC	Male	III,IV	+0.542	<.001	8	view →
LUAD	Female	II,III,IV	+0.407	<.001	8	view →
THCA	Female	All	+0.319	<.001	6	view →
BRCA	All	All	+0.221	<.001	6	view →
CHOL	Male	All	+1.470	<.001	3	view →
LUSC	All	All	+0.271	<.001	3	view →
UCEC	All	All	+0.512	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

TAF10–KIRC

Open the KIRC breakdown →