TAF10

Across TCGA pan-cancer cohorts, TAF10 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TAF10 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TAF10 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TAF10 expression acts as an unfavorable survival marker, although some lineages such as GBM and LSCC show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where TAF10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.783	0.906	.016	8	view →
CCRCC	DFS	Quartile	All	0.837	0.971	.018	7	view →
LUAD	OS	Quartile	All	0.905	1.000	.012	6	view →
UCEC	DFS	Tertile	All	0.875	0.977	.034	4	view →
GBM	OS	Tertile	All	0.891	0.744	.013	3	view →
LSCC	DFS	Tertile	III,IV	0.826	0.476	.036	3	view →
PDAC	OS	Quartile	All	0.996	0.826	.012	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TAF10–HNSC (OS)

Open the HNSC breakdown →