TAF1

Across TCGA pan-cancer cohorts, TAF1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TAF1 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TAF1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TAF1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

PDAC, LUAD, and CCRCC are the cancer types where TAF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.981	0.771	.007	11	view →
LUAD	DFS	Median	All	0.480	0.710	.020	7	view →
CCRCC	DFS	Median	All	0.858	0.962	.010	7	view →
UCEC	DFS	Tertile	III,IV	0.409	0.850	.043	4	view →
LSCC	OS	Median	All	0.777	1.000	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TAF1–PDAC (OS)

Open the PDAC breakdown →