TAF1

Across TCGA pan-cancer cohorts, TAF1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of TAF1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TAF1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAF1 is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

COAD, HNSC, and LIHC are the cancer types where TAF1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAF1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.483	<.001	9	view →
HNSC	All	All	+0.625	<.001	8	view →
LIHC	All	II,III,IV	+0.722	<.001	7	view →
CHOL	All	All	+1.746	<.001	5	view →
THCA	All	All	−0.390	.002	5	view →
READ	All	III,IV	+0.855	.005	4	view →
STAD	Male	II,III,IV	+0.815	.008	4	view →
KIRC	All	All	+0.254	.003	3	view →
UCEC	All	All	−0.627	.001	2	view →
KICH	All	All	−0.392	.032	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

TAF1–COAD

Open the COAD breakdown →