TAF1

Across TCGA cell cohorts, TAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,916 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TAF1-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Positive regulation of telomerase RNA localization to Cajal body, and Regulation of protein autoubiquitination. Each is linked with TAF1 in more than 18 cancer types. Because this analysis shows association rather than direction, both TAF1-to-partner and partner-to-TAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by TAF1-low versus TAF1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF1→partner) and Y-score (partner→TAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.227	+1.080	<.001	<.001	3	19
BONE	Positive regulation of telomerase RNA localization to Cajal body →	+0.131	+0.774	<.001	.001	3	17
STOMACH	Regulation of protein autoubiquitination →	+0.207	+0.863	<.001	<.001	2	17
BONE	Regulation of DNA-templated transcription initiation →	+0.072	+0.869	.002	.003	3	16
BONE	mRNA catabolic process →	+0.068	+0.789	<.001	.002	3	16
UPPER_AERODIGESTIVE_TRACT	mRNA export from nucleus →	+0.117	+1.256	.002	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,916 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by TAF1 expression — BLOOD_Myeloma

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