TAF1

Across TCGA cell cohorts, TAF1 mutation is significantly associated with the RNA expression of many other genes, with 712 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAF1-associated genes across cancer lineages are OR6J1, OR5J2, and OR4N2. Each is linked with TAF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF1-to-partner and partner-to-TAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6J1 grouped by TAF1-low versus TAF1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF1→partner) and Y-score (partner→TAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR6J1 →	+0.005	+3.510	.009	.003	3	2
LUNG_NSCLC_LUAD	OR5J2 →	+0.066	+4.266	<.001	.004	3	2
BLOOD_Lymphoma	OR4N2 →	+0.013	+4.058	<.001	.009	3	2
BLOOD_Lymphoma	PRAMEF10 →	+0.022	+4.662	<.001	.003	3	2
BREAST	RNASE3 →	+0.060	+3.415	<.001	.004	3	2
BREAST	KLRF2 →	+0.031	+3.781	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 712 associations by consensus.

OR6J1 by TAF1 expression — SKIN

Explore this box plot interactively →