TADA2B

Across TCGA patient cohorts, TADA2B mutation is significantly associated with the RNA expression of many other genes, with 349 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TADA2B-associated genes across cancer lineages are MTCO3P20, VTRNA3-1P, and FCF1P4. Each is linked with TADA2B in more than 1 cancer types. Because this analysis shows association rather than direction, both TADA2B-to-partner and partner-to-TADA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCO3P20 grouped by TADA2B-low versus TADA2B-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TADA2B→partner) and Y-score (partner→TADA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MTCO3P20 →	+0.183	+5.174	<.001	.001	3	2
CESC	VTRNA3-1P →	+0.314	+4.539	<.001	.008	3	2
CESC	FCF1P4 →	+0.189	+5.837	<.001	.001	3	2
CESC	POLR2DP1 →	+0.091	+4.669	<.001	.007	3	2
LUAD	RNU6-1213P →	+0.508	+7.930	<.001	.008	3	2
PRAD	RNU6-939P →	+0.279	+7.939	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 349 associations by consensus.

MTCO3P20 by TADA2B expression — LIHC

Explore this box plot interactively →