TADA2B

Across TCGA pan-cancer cohorts, TADA2B RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of TADA2B’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TADA2B RNA is repressed in tumor relative to normal tissue. In most cancer types TADA2B is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

COAD, THCA, and READ are the cancer types where TADA2B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TADA2B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	−0.604	<.001	11	view →
THCA	All	II,III,IV	−0.412	<.001	9	view →
READ	All	II,III,IV	−0.690	<.001	7	view →
LIHC	Female	II,III,IV	+0.787	<.001	6	view →
LUSC	All	II,III,IV	−0.397	<.001	6	view →
KIRC	Male	II,III,IV	−0.338	.003	6	view →
BLCA	All	All	−0.314	.034	4	view →
LUAD	Female	All	−0.199	.008	4	view →
CHOL	All	All	+0.836	<.001	3	view →
KIRP	All	All	−0.335	.001	3	view →
UCEC	All	All	−0.344	.021	2	view →
STAD	Female	III,IV	−0.520	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

TADA2B–COAD

Open the COAD breakdown →