TADA2B

Across TCGA cell cohorts, TADA2B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible TADA2B-associated genes across cancer lineages are IL17A, XPNPEP2, and SPATA3. Each is linked with TADA2B in more than 1 cancer types. Because this analysis shows association rather than direction, both TADA2B-to-partner and partner-to-TADA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL17A grouped by TADA2B-low versus TADA2B-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TADA2B→partner) and Y-score (partner→TADA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	IL17A →	+0.005	+4.614	<.001	.004	3	1
PANCREAS	XPNPEP2 →	+0.046	+4.011	<.001	.009	3	1
PANCREAS	SPATA3 →	+0.277	+4.614	<.001	.004	3	1
PANCREAS	ETV3L →	+0.045	+4.011	.002	.009	3	1
CNS	F9 →	+0.042	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

IL17A by TADA2B expression — PANCREAS

Explore this box plot interactively →