TADA1

Across TCGA cell cohorts, TADA1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TADA1-associated genes across cancer lineages are CELA2B, MSGN1, and OR10W1. Each is linked with TADA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TADA1-to-partner and partner-to-TADA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CELA2B grouped by TADA1-low versus TADA1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TADA1→partner) and Y-score (partner→TADA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CELA2B →	+0.049	+4.467	<.001	.004	3	1
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	OR10W1 →	+0.012	+3.977	<.001	.001	3	1
LARGE_INTESTINE	TFDP3 →	+0.020	+3.196	.001	.007	3	1
LARGE_INTESTINE	TAFA1 →	+0.274	+3.688	<.001	.002	3	1
LARGE_INTESTINE	C14orf180 →	+0.181	+4.477	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

CELA2B by TADA1 expression — SKIN

Explore this box plot interactively →