TACO1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TACO1 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible TACO1-associated genes across cancer lineages are LINC01815, RNU6-684P, and CSPG4P1Y. Each is linked with TACO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TACO1-to-partner and partner-to-TACO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01815 grouped by TACO1-low versus TACO1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TACO1→partner) and Y-score (partner→TACO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCALINC01815 →+0.652+5.914<.001<.00132
BRCARNU6-684P →+0.339+8.471<.001.00531
BRCACSPG4P1Y →+0.044+9.057<.001.00331
BLCALINC00400 →+0.073+5.018<.001.00431
BLCALIPT1P1 →+0.041+5.814<.001.00131
BLCAMTCO3P2 →+0.297+5.213<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

LINC01815 by TACO1 expression — BLCA

Box plot of LINC01815 in TACO1-low vs TACO1-high samples in BLCA.

Explore this box plot interactively →

Exploration