TACC3

Across TCGA patient cohorts, TACC3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,660 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TACC3-associated genes across cancer lineages are DDIAS, PARPBP, and FAM72B. Each is linked with TACC3 in more than 8 cancer types. Because this analysis shows association rather than direction, both TACC3-to-partner and partner-to-TACC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TACC3 versus DDIAS in OV, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TACC3→partner) and Y-score (partner→TACC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DDIAS →	+1.022	+0.777	<.001	<.001	3	9
UCEC	PARPBP →	+0.855	+0.662	<.001	<.001	3	9
COAD	FAM72B →	+0.952	+0.584	.001	.003	3	9
UCEC	NCAPG →	+1.218	+0.713	<.001	<.001	3	8
BRCA	FOXM1 →	+1.436	+0.620	<.001	<.001	3	8
BRCA	CDCA3 →	+1.007	+0.524	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,660 associations by consensus.

TACC3 vs DDIAS — OV

Explore this scatter interactively →