TACC2

Across TCGA patient cohorts, TACC2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,678 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TACC2-associated genes across cancer lineages are NSMCE4A, PANK1, and ARHGEF37. Each is linked with TACC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both TACC2-to-partner and partner-to-TACC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TACC2 versus NSMCE4A in LSCC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TACC2→partner) and Y-score (partner→TACC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NSMCE4A →	+0.437	+0.480	<.001	<.001	3	7
CCRCC	PANK1 →	+0.893	+0.237	<.001	.007	3	6
CCRCC	ARHGEF37 →	+0.831	+0.328	.002	.001	3	6
CCRCC	S1PR2 →	-0.533	-0.284	<.001	.001	3	6
LSCC	ABLIM1 →	+0.790	+0.536	<.001	<.001	3	6
HNSC	GXYLT2 →	-1.096	-0.311	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,678 associations by consensus.

TACC2 vs NSMCE4A — LSCC

Explore this scatter interactively →