TACC2

Across TCGA cell cohorts, TACC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,556 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TACC2-associated GO terms across cancer lineages are Regulation of plasma cell differentiation, Negative regulation of CD8-positive, alpha-beta T cell differentiation, and Negative regulation of fatty acid transport. Each is linked with TACC2 in more than 7 cancer types. Because this analysis shows association rather than direction, both TACC2-to-partner and partner-to-TACC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of plasma cell differentiation grouped by TACC2-low versus TACC2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TACC2→partner) and Y-score (partner→TACC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of plasma cell differentiation →	+0.120	+1.035	<.001	<.001	3	8
OESOPHAGUS	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.223	+1.201	.001	<.001	3	8
LARGE_INTESTINE	Negative regulation of fatty acid transport →	-0.210	-1.475	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Astral microtubule organization →	+0.098	+0.946	.003	.005	3	7
OVARY	Copper ion export →	-0.206	-1.114	<.001	.001	3	7
OESOPHAGUS	Negative regulation of NK T cell activation →	+0.230	+1.402	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,556 associations by consensus.

Regulation of plasma cell differentiation by TACC2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →