TAC4

Across TCGA patient cohorts, TAC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,407 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TAC4-associated proteins across cancer lineages are THOC1, THOC1_S560, and ACIN1. Each is linked with TAC4 in more than 3 cancer types. Because this analysis shows association rather than direction, both TAC4-to-partner and partner-to-TAC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAC4 versus THOC1 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TAC4→partner) and Y-score (partner→TAC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	THOC1 →	+0.348	+0.642	<.001	<.001	3	4
LSCC	THOC1_S560 →	+0.424	+0.501	<.001	.002	3	4
LSCC	ACIN1 →	+0.207	+0.601	<.001	<.001	3	4
LSCC	NACC1 →	+0.327	+0.771	<.001	<.001	3	4
LSCC	NONO →	+0.144	+0.485	.001	<.001	3	4
LSCC	SF3B3 →	+0.292	+0.791	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,407 associations by consensus.

TAC4 vs THOC1 — LSCC

Explore this scatter interactively →