TAC3

Across TCGA patient cohorts, TAC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,541 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TAC3-associated proteins across cancer lineages are SMPD3, SMPD3_S209, and ADNP_S98. Each is linked with TAC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAC3-to-partner and partner-to-TAC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAC3 versus SMPD3 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TAC3→partner) and Y-score (partner→TAC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMPD3 →	+0.561	+1.279	<.001	<.001	3	3
PDAC	SMPD3_S209 →	+1.050	+0.455	<.001	.001	3	3
LSCC	ADNP_S98 →	+0.537	+0.262	.004	.006	3	3
LSCC	SART3 →	+0.253	+0.269	<.001	.003	3	3
GBM	ARRB1 →	+0.313	+1.370	.006	.001	3	2
UCEC	SELENBP1 →	+0.479	+0.496	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,541 associations by consensus.

TAC3 vs SMPD3 — GBM

Explore this scatter interactively →