TAC3

Across TCGA patient cohorts, TAC3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,041 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TAC3-associated genes across cancer lineages are SNRPD3, PRODH, and CYTH4. Each is linked with TAC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAC3-to-partner and partner-to-TAC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAC3 versus SNRPD3 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAC3→partner) and Y-score (partner→TAC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.321	+0.574	.003	.004	3	1
GBM	PRODH →	+0.608	+0.559	.008	.006	3	1
GBM	CYTH4 →	-0.623	-0.666	.004	.006	3	1
GBM	SEPTIN3 →	+1.368	+1.048	<.001	<.001	3	1
GBM	NEFH →	+1.064	+0.706	.001	.003	3	1
GBM	HMOX1 →	-1.084	-0.925	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,041 associations by consensus.

TAC3 vs SNRPD3 — GBM

Explore this scatter interactively →