TAC3

Across TCGA cell cohorts, TAC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,733 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAC3-associated GO terms across cancer lineages are Leukocyte aggregation, Fibrinolysis, and Regulation of fibrinolysis. Each is linked with TAC3 in more than 5 cancer types. Because this analysis shows association rather than direction, both TAC3-to-partner and partner-to-TAC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leukocyte aggregation grouped by TAC3-low versus TAC3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAC3→partner) and Y-score (partner→TAC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Leukocyte aggregation →	-0.464	-0.230	.007	.006	3	6
LUNG_NSCLC_LUSC	Fibrinolysis →	-1.525	-0.314	.001	.008	3	5
LUNG_NSCLC_LUSC	Regulation of fibrinolysis →	-0.395	-0.235	<.001	.008	3	5
BONE	Regulation of actin filament-based movement →	+0.131	+0.943	.001	.008	3	5
BLOOD_Myeloma	Positive regulation of amine metabolic process →	-0.198	-0.120	.001	.003	2	6
LUNG_SCLC	Outer mitochondrial membrane organization →	+0.087	+2.098	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,733 associations by consensus.

Leukocyte aggregation by TAC3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →