TAC3

Across TCGA cell cohorts, TAC3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,273 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAC3-associated genes across cancer lineages are TMEM190, HMGCS1, and MTMR6. Each is linked with TAC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TAC3-to-partner and partner-to-TAC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAC3 versus TMEM190 in CNS, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAC3→partner) and Y-score (partner→TAC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TMEM190 →	+0.853	+1.382	.002	.008	3	4
OVARY	HMGCS1 →	-0.829	-1.150	.004	.003	3	3
STOMACH	MTMR6 →	+0.923	+1.936	.007	.009	3	3
LUNG_SCLC	AVL9 →	+0.743	+1.440	.004	.007	3	3
CNS	TIMM17B →	+0.858	+1.243	<.001	<.001	3	3
CNS	ACTR1A →	+0.576	+1.315	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,273 associations by consensus.

TAC3 vs TMEM190 — CNS

Explore this scatter interactively →