TAAR8

Across TCGA patient cohorts, TAAR8 mutation is significantly associated with the RNA expression of many other genes, with 1,037 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAAR8-associated genes across cancer lineages are RNA5SP193, OR5D3P, and LCE4A. Each is linked with TAAR8 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAAR8-to-partner and partner-to-TAAR8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP193 grouped by TAAR8-low versus TAAR8-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAAR8→partner) and Y-score (partner→TAAR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP193 →	+0.154	+4.584	<.001	.004	3	2
COAD	OR5D3P →	+0.074	+5.917	<.001	.001	3	1
COAD	LCE4A →	+0.159	+6.142	<.001	<.001	3	1
COAD	OR2T3 →	+0.081	+6.409	<.001	<.001	3	1
COAD	RNA5SP442 →	+0.702	+4.893	<.001	.005	3	1
COAD	RNU6-650P →	+0.499	+5.392	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,037 associations by consensus.

RNA5SP193 by TAAR8 expression — LUSC

Explore this box plot interactively →