TAAR8

Across TCGA pan-cancer cohorts, TAAR8 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated TAAR8 data layer compared with 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TAAR8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TAAR8 expression acts as an unfavorable survival marker, although some lineages such as SCLC and KIRP show a favorable association.

COAD, UCEC, and KICH are the cancer types where TAAR8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	II,III,IV	0.503	0.858	<.001	144	view →
UCEC	DFS	Tertile	All	0.503	0.666	<.001	108	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
BLCA	OS	Tertile	All	0.173	0.698	<.001	90	view →
LIHC	DFS	Tertile	All	0.229	0.569	<.001	87	view →
HNSC	OS	Tertile	II,III,IV	0.001	0.712	<.001	72	view →
KIRC	OS	Quartile	All	0.737	0.823	.006	58	view →
LUAD	DFS	Tertile	All	0.647	0.795	.004	51	view →
SCLC	DFS	Tertile	II,III,IV	1.000	0.483	.009	48	view →
TGCT	DFS	Tertile	All	0.681	0.844	.035	12	view →
KIRP	DFS	Tertile	IV	0.800	0.522	.047	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

TAAR8–COAD (OS)

Open the COAD breakdown →