TAAR8

Across TCGA cell cohorts, TAAR8 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAAR8-associated genes across cancer lineages are CLDN17 and FAM205A. Each is linked with TAAR8 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAAR8-to-partner and partner-to-TAAR8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLDN17 grouped by TAAR8-low versus TAAR8-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAAR8→partner) and Y-score (partner→TAAR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CLDN17 →	+0.018	+5.228	<.001	.005	3	1
LARGE_INTESTINE	FAM205A →	+0.026	+3.614	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CLDN17 by TAAR8 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →