TAAR5

Across TCGA patient cohorts, TAAR5 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAAR5-associated genes across cancer lineages are EGFR_pY1068, eIF4E, and Ku80. Each is linked with TAAR5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAAR5-to-partner and partner-to-TAAR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by TAAR5-low versus TAAR5-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAAR5→partner) and Y-score (partner→TAAR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EGFR_pY1068 →	-0.376	-2.991	.027	.036	3	2
UCEC	eIF4E →	+0.184	+3.000	.045	.036	3	1
UCEC	Ku80 →	+0.245	+2.820	.017	.001	3	1
UCEC	MEK1 →	+0.396	+3.584	.013	.002	3	1
UCEC	Notch1 →	+0.226	+2.807	<.001	.003	3	1
UCEC	p62 Lck ligand →	+0.438	+2.469	.002	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

EGFR_pY1068 by TAAR5 expression — COAD

Explore this box plot interactively →