TAAR1

Across TCGA patient cohorts, TAAR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,527 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible TAAR1-associated GO terms across cancer lineages are Tissue homeostasis, Epithelial cell development, and Leukocyte adhesion to vascular endothelial cell. Each is linked with TAAR1 in more than 12 cancer types. Because this analysis shows association rather than direction, both TAAR1-to-partner and partner-to-TAAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tissue homeostasis grouped by TAAR1-low versus TAAR1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAAR1→partner) and Y-score (partner→TAAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Tissue homeostasis →	+0.050	+0.589	<.001	<.001	3	12
STAD	Epithelial cell development →	+0.042	+0.422	<.001	<.001	2	13
ESCA	Leukocyte adhesion to vascular endothelial cell →	+0.055	+0.621	<.001	.004	2	12
ESCA	Maintenance of blood-brain barrier →	+0.073	+0.713	<.001	<.001	3	11
STAD	Response to endoplasmic reticulum stress →	+0.043	+0.392	<.001	<.001	3	11
ESCA	Post-translational protein targeting to endoplasmic reticulum membrane →	+0.052	+0.522	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,527 associations by consensus.

Tissue homeostasis by TAAR1 expression — ESCA

Explore this box plot interactively →