TAAR1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TAAR1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAAR1-associated genes across cancer lineages are GPHA2 and PLA2G2E. Each is linked with TAAR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAAR1-to-partner and partner-to-TAAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPHA2 grouped by TAAR1-low versus TAAR1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAAR1→partner) and Y-score (partner→TAAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEGPHA2 →+0.267+3.592.004.00631
LARGE_INTESTINEPLA2G2E →+0.251+3.556<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GPHA2 by TAAR1 expression — LARGE_INTESTINE

Box plot of GPHA2 in TAAR1-low vs TAAR1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration