SZT2-AS1

Across TCGA patient cohorts, SZT2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,988 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SZT2-AS1-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Regulation of double-strand break repair, and Negative regulation of protein K63-linked ubiquitination. Each is linked with SZT2-AS1 in more than 23 cancer types. Because this analysis shows association rather than direction, both SZT2-AS1-to-partner and partner-to-SZT2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by SZT2-AS1-low versus SZT2-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SZT2-AS1→partner) and Y-score (partner→SZT2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of DNA metabolic process →	+0.038	+0.250	<.001	<.001	3	24
ESCA	Regulation of double-strand break repair →	+0.036	+0.219	<.001	<.001	3	24
KIRC	Negative regulation of protein K63-linked ubiquitination →	+0.046	+0.182	<.001	<.001	3	23
ESCA	Negative regulation of mRNA processing →	+0.052	+0.186	<.001	<.001	3	23
ESCA	Regulation of DNA repair →	+0.036	+0.216	<.001	<.001	3	23
ESCA	Positive regulation of double-strand break repair →	+0.044	+0.225	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,988 associations by consensus.

Positive regulation of DNA metabolic process by SZT2-AS1 expression — ESCA

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