SZT2-AS1

Across TCGA pan-cancer cohorts, SZT2-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SZT2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SZT2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SZT2-AS1 expression acts as an unfavorable survival marker, although some lineages such as THYM and UCS show a favorable association.

KIRC, LIHC, and ACC are the cancer types where SZT2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	All	0.504	0.707	<.001	123	view →
LIHC	OS	Median	All	0.396	0.596	<.001	79	view →
ACC	OS	Median	All	0.660	0.919	<.001	58	view →
MESO	OS	Quartile	II,III,IV	0.270	0.479	.006	38	view →
THYM	DFS	Tertile	III,IV	1.000	0.222	.001	28	view →
UCS	DFS	Tertile	IV	0.932	0.419	.024	24	view →
LUAD	DFS	Median	IV	0.506	0.850	.006	24	view →
LGG	DFS	Tertile	All	0.645	0.803	<.001	22	view →
SKCM	OS	Tertile	IV	0.856	0.497	.007	18	view →
PRAD	DFS	Quartile	All	0.836	0.959	<.001	18	view →
CHOL	OS	Quartile	All	1.000	0.104	.006	15	view →
BRCA	DFS	Quartile	IV	0.359	0.846	.005	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SZT2-AS1–KIRC (DFS)

Open the KIRC breakdown →