SYTL4

Across TCGA patient cohorts, SYTL4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,358 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SYTL4-associated proteins across cancer lineages are SYTL4_S74, SYTL4_S221, and SYTL4_S296. Each is linked with SYTL4 in more than 9 cancer types. Because this analysis shows association rather than direction, both SYTL4-to-partner and partner-to-SYTL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYTL4 versus SYTL4_S74 in BRCA, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL4→partner) and Y-score (partner→SYTL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SYTL4_S74 →	+1.478	+1.510	<.001	<.001	3	10
OV	SYTL4_S221 →	+1.663	+1.425	.004	.001	3	9
BRCA	SYTL4_S296 →	+1.027	+1.342	<.001	<.001	3	9
BRCA	NOC2L →	-0.285	-0.722	<.001	<.001	3	5
UCEC	PALLD →	+0.882	+1.035	<.001	<.001	3	5
GBM	SEPTIN2 →	+0.268	+1.189	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,358 associations by consensus.

SYTL4 vs SYTL4_S74 — BRCA

Explore this scatter interactively →