SYTL4

Across TCGA cell cohorts, SYTL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,113 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SYTL4-associated GO terms across cancer lineages are Organelle disassembly, Striated muscle contraction, and Vacuolar transport. Each is linked with SYTL4 in more than 9 cancer types. Because this analysis shows association rather than direction, both SYTL4-to-partner and partner-to-SYTL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle disassembly grouped by SYTL4-low versus SYTL4-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL4→partner) and Y-score (partner→SYTL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Organelle disassembly →	+0.045	+1.728	.003	<.001	3	10
SOFT_TISSUE	Striated muscle contraction →	+0.098	+1.580	<.001	<.001	3	9
OESOPHAGUS	Vacuolar transport →	+0.061	+1.948	<.001	<.001	3	8
BREAST	Hormone-mediated signaling pathway →	+0.033	+0.985	.009	.009	3	8
URINARY_TRACT	Negative regulation of supramolecular fiber organization →	+0.069	+1.445	.006	<.001	3	8
PANCREAS	Regulation of cell-substrate adhesion →	+0.069	+1.440	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,113 associations by consensus.

Organelle disassembly by SYTL4 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →