SYTL3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SYTL3 mutation is significantly associated with the RNA expression of many other genes, with 3,570 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYTL3-associated genes across cancer lineages are RNA5SP411, TSNAX-DISC1, and MIR8055. Each is linked with SYTL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYTL3-to-partner and partner-to-SYTL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by SYTL3-low versus SYTL3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL3→partner) and Y-score (partner→SYTL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP411 →+0.996+1.908<.001<.00132
COADTSNAX-DISC1 →+0.057+3.761.002.00332
COADMIR8055 →+0.733+3.589.002.00632
CESCGSTA6P →+0.130+5.010<.001.00932
CESCUBE2V1P4 →+0.134+5.103<.001.00832
SKCMELAVL4-AS1 →+0.210+2.369<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,570 associations by consensus.

RNA5SP411 by SYTL3 expression — UCEC

Box plot of RNA5SP411 in SYTL3-low vs SYTL3-high samples in UCEC.

Explore this box plot interactively →

Exploration