SYT9

Across TCGA patient cohorts, SYT9 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYT9-associated genes across cancer lineages are FASN, Src_pY527, and SCD. Each is linked with SYT9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SYT9-to-partner and partner-to-SYT9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by SYT9-low versus SYT9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT9→partner) and Y-score (partner→SYT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.327	+2.000	.034	.030	3	3
UCEC	Src_pY527 →	-0.364	-3.169	.031	.018	3	3
SKCM	SCD →	+0.177	+3.050	.005	.016	3	2
SKCM	c-Kit →	-0.625	-3.169	.027	.017	3	2
UCEC	A-Raf_pS299 →	-0.098	-2.584	.037	.010	3	2
UCEC	FOXO3a_pS318_S321 →	-0.101	-1.797	.038	.025	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

FASN by SYT9 expression — UCEC

Explore this box plot interactively →