SYT9

Across TCGA cell cohorts, SYT9 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SYT9-associated genes across cancer lineages are TSPAN16, CRYZL1, and OR51G2. Each is linked with SYT9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYT9-to-partner and partner-to-SYT9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPAN16 grouped by SYT9-low versus SYT9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT9→partner) and Y-score (partner→SYT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TSPAN16 →	+0.023	+3.347	<.001	.005	3	1
SKIN	CRYZL1 →	+0.472	+3.215	.006	.009	3	1
LUNG_NSCLC_LUAD	OR51G2 →	+0.054	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	MAGEB10 →	+0.029	+4.544	<.001	.003	3	1
SKIN	EEF1E1 →	+0.625	+3.125	<.001	.008	2	1
SKIN	PARVG →	+1.311	+3.215	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

TSPAN16 by SYT9 expression — LARGE_INTESTINE

Explore this box plot interactively →